Kinetic Benchmarking Reveals the Competence of Prenyl Groups in Ring-Closing Metathesis.
Org Lett
; 19(19): 5332-5335, 2017 10 06.
Article
in En
| MEDLINE
| ID: mdl-28933551
ABSTRACT
A series of prenyl-containing malonates are kinetically benchmarked against the standard allyl-containing congeners using a ruthenium benzylidene precatalyst for ring-closing metatheses. The prenyl grouping is found to be a superior acceptor olefin compared to an allyl group in RCM processes with ruthenium alkylidenes derived from terminal alkenes. The prenyl group is also found to be a highly competent acceptor for a ruthenium alkylidene derived from a 1,1-disubstituted olefin in a RCM process.
Full text:
1
Collection:
01-internacional
Database:
MEDLINE
Language:
En
Journal:
Org Lett
Journal subject:
BIOQUIMICA
Year:
2017
Document type:
Article
Affiliation country: